I've seen this discussed before but I couldn't find it in a search so here it goes again. I've developed a fairly sharp and localized pain in the wrist of my fretting hand, on the bottom side (pinky side). I've been hoping it is not due to playing but I'm beginning to suspect otherwise. I was away from home for four days last week and only brought a guitar. I played for hours and my wrist was fine. Got back home, picked up the mando for a bit and wrist pain came back. I play a Collings MT2 with the sharp V neck. I've read here before that others had similar pain and switched to a rounded neck and the problem went away. Problem is that I play left handed and it's not very easy to play other instruments.
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