I have made emandos with both of those pickups. The Dimarzio units seem a bit more mellow than the SD - a little lower output for the same circuit configuration. The SD have a bit edgier sound - seems to me to be more favorable for distortion effects. I use the Dimarzios on my 8 string to get a little cleaner, more mandolin-like sound, and the SDs on my 5 string. I have the Dimarzios on my 4 string, but am considering changing to the 'hotter' SD pickups there also.
...do guitar players get GAS?